Scientific journal
Balanced diet, nutritional supplements and biostimulants
ISSN 2414-1054
ISSN 2414-1054
COMPARATIVE ASPECTS OF PATHOGENESIS OF INTESTINAL INSUFFICIENCY SYNDROME IN ACUTE INTESTINAL OBSTRUCTION AND PERITONITIS IN EXPERIMENT
Uryadov S.E. 1
Stepanyan A.T. 1
Stekolnikov N.Yu. 2
Odnokozova Yu.S. 2
1 Samara Medical Institute “REAVIZ” Saratov branch Saratov
2 Saratov State Medical University VI Razumovsky
226 KB
Summary. The problem of timely diagnosis of postoperative complications is one of the important in urgent surgery. To solve this problem is to actively search for optimal algorithms diagnostic procedures or laboratory markers. In recent years, as the leading pathogenetic mechanism, causing occurrence of abdominal sepsis syndrome assigned intestinal failure and the consequences of endotoxin aggression. The paper presents experimental given the dynamics of the content level of LPS depending on the type of postoperative complications and postoperative course. Shown that peritonitis from the outset characterized by high levels of LPS, whereas with prolonged postoperative paresis 3 stage intestinal insufficiency syndrome developed by the end of the third day. In addition, the sharp increase in the LPS may serve as a diagnostic factor in the development of postoperative peritonitis. Conclusions. Determining the level of the dynamics of LPS in the postoperative period can be an effective method of early diagnosis of postoperative peritonitis.