Neschislyaev V.A. 1
Archakova E.G. 1
Orlova E.V. 1
Bakhtin I.A. 1
1 Perm branch “BIOMED” of MICROGEN State Unitary Company
The complex biological preparation “Bifibad” containing bifidobacteria in powder form in a sachet intended for intestinal dysbiosis correction was developed. The production strain Bifidobacterium bifidum 1 was used. The procedure of dry biomass obtaining provides a full retention of bifidobacteria exametabolite complex, that increases the therapeutic potential of the probiotic component. The preparation includes microcrystalline cellulose (dietary fiber with prebiotic properties) that allows to consider “Bifibad” as symbiotic. The drug possesses required biological and technological properties. The carried out studies have allowed to confirm the optimum shelf life for the powder form of the drug - one year, and have also shown the ability to use in the technology of “Bifibad” buflen as material for primary package that ensured synbiotic stability during the entire period of observation.