Latyshev D.Y. 1
Lobanov Y.F. 1
Danilov A.N. 2
Danilov D.A. 2
Pechkina K.G. 2
1 GBOU VPO «Altay state medical university of the Ministry of Public Health and Social Development of Russia»
2 КГБУЗ «Children’s city hospital № 1»
The analysis of the prevalence of serological markers of celiac disease in 56 children aged 6 to 16 years with a diagnosis of irritable bowel syndrome with diarrhea that is associated with the results of the morphometric study. In 28,5 % of children with irritable bowel syndrome have been identifi ed serological markers of celiac disease, mainly antibodies to gliadin class G, and this level of increase was low, and was about four standards, antibodies to tissue transglutaminase revealed only 6,6 %. Increasing the level of antibodies were detected in 38,5 % of the boys (the number of surveyed male), and 23,5 % of girls, but statistically not signifi cant differences (p = 0,548). According to the morphological study of signs of mucosal atrophy haven’t been identifi ed, which may indicate involvement in the development of irritable bowel syndrome with diarrhea than the immune mechanisms of gluten intolerance.