Anshakova V.V. 1
Kershengoltc B.M. 1, 2
Koryakina V.V. 3
Ivanova I.K. 1, 3
1 North-Eastern Federal University named after M.K. Ammosov
2 Institute of biological problems of permafrost SB RAS
3 Institute of Oil and Gas Problems
The mechanochemical technology for producing of high-performance solid-state biocomplexes processing without solvent in one technological stage based on «universal active fi ller» which is a polymer lichen b-oligosaccharide matrix with different kind of API (known pharmaceuticals, physiologically active substances of herbs) is developed. Impact-abrasive effect with additives of solid-state chemical reagents (eg. Salts), followed by changes in the chemical composition of the components of plant material along with the destruction of cell walls. It is a result of breaking a number of chemical bonds (even such strong as β-glycoside), and of chemical reactions, including to the formation of some very important API just (namely) in the process of mechanochemical processing of raw materials.The application of «solvent-free» processes based on natural oligosaccharides prolongs of the operation of API and increases of its biological effect in a few times, while reducing the dose and toxicity.