Murakova G.R. 1
Merkulova O.A. 1
Rodina O.P. 2
Vodopjanova O.A. 2
Antropova N.V. 2
1 State Health Care Establishment “Regional Hospital by Burdenko N.N.” Penza
2 FSGFE “ Penza State University” Penza
The experience of practical use of Tiolipon medication in diabetic neuropathy treatment in patients with type II diabetes mellitus was studied. The severity of neuropathy complaints and the other Symptoms of diabetic neuropathy was assessed using the scale of neurological symptoms TSS, NIS-LL, using sequential oral administration and intravenous administration of Tiolipon on top of standard hypoglycemic therapy. The level of peripheral nerves function disorder and nervous prolongation was detected by electroneuromyography study. TTS und NDS indexes got better in comparison with control group. The reduction of severity of positive neuropathy Symptoms and threshold of vibrational soreness was found out. The improvement of sensory function in management with Tiolipon was found out as well. According to electroneuromyographic studies high velocity of excitation propagation was detected. Range increase M-response n.tibialis and n.peroneus decrease of residual latency on n.abductor pollicis brevis in control patients group were found out as well.