Bystrova M.N. 1
1 Tver state medical academy
Comparative study of the influence of extraction modes on the final contents of active ingredients in preparations of sedative collection № 3 was carried out. The results of the research showed that the greatest amount of final contents from vegetative raw materials of the main groups of biologically active substances is provided while preparing extraction preparations (the extract of dry and water-alcoholic extraction) of sedative collection № 3. It is established that the contents of flavonoids in water-alcoholic extraction from collecting was on the average 3,3 times (р<0,05) more than in the solution of dry extract and on the average 7,5 times (р<0,05) more than in the infusion made according to the instruction on medical application. The content of tannins in water-alcoholic extraction was on the average 1,2 times (R р<0,05) higher, than in the solution of dry extract. The amount of free organic acids most of all was in the solution of dry extract and made up 1,08±0,11 % that on the average was 4,2 times (р<0,05) and 5 times (р<0,05) higher, than in the tincture and infusion respectively.